| 发明名称 |
DIFFERENTIAL EXPRESSION OF MICRORNAS IN NONFAILING VERSUS FAILING HUMAN HEARTS |
| 摘要 |
The present invention discloses specific miRNAs as novel biomarkers and therapeutic targets in the treatment of heart failure. Methods of treating or preventing heart failure in a subject by administering mimics or inhibitors of these particular miRNAs are disclosed. A method of diagnosing or prognosing heart failure in a subject by determining the level of expression of one or more miRNAs is also described.
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| 申请公布号 |
US2010267804(A1) |
申请公布日期 |
2010.10.21 |
| 申请号 |
US20080669422 |
申请日期 |
2008.07.18 |
| 申请人 |
PORT JONATHAN DAVID;SUCHAROV CARMEN;BRISTOW MICHAEL R |
发明人 |
PORT JONATHAN DAVID;SUCHAROV CARMEN;BRISTOW MICHAEL R. |
| 分类号 |
A61K31/7125;A61K31/7105;A61K31/712;A61P9/00;A61P9/04;C12N5/071;C12Q1/68;C40B30/00;G01N33/48 |
主分类号 |
A61K31/7125 |
| 代理机构 |
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