发明名称 |
COMBINATION THERAPY USING AN ANTI-EGFR AGENT(S) AND IGF-1R SPECIFIC INHIBITORS |
摘要 |
The combination of an IGF-1R antagonist such as a humanized antibody and an anti-proliferative drug is described. In a preferred embodiment, the present invention describes the combination of an IGF-1R antibody and an anti-proliferative drug belonging to the EGFR-inhibitor class, which is preferably erlotinib. The combination according to the present invention is useful for the treatment of tumours, including IGF-1R and /or EGFR mediated or dependent tumours.
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申请公布号 |
CA2757730(A1) |
申请公布日期 |
2010.10.21 |
申请号 |
CA20102757730 |
申请日期 |
2010.04.06 |
申请人 |
MERCK SHARP & DOHME CORP. |
发明人 |
SATHYANARAYANAN, SRIRAM;KASIBHATLA, SHAILAJA;WINTER, CHRISTOPHER;CHASTAIN, MICHAEL |
分类号 |
A61K39/395;A61K31/517 |
主分类号 |
A61K39/395 |
代理机构 |
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