| 发明名称 |
HISTONE MODIFICATION PATTERNS FOR CLINICAL DIAGNOSIS AND PROGNOSIS OF CANCER |
| 摘要 |
The present invention provides methods of diagnosing and providing a prognosis and therapy for cancer including, but not limited to, pancreatic cancer and responsiveness to thymidylate synthase inhibitor (e.g., 5-FU) therapy, by identifying cancers with altered histone modification patterns selected from the group consisting of H3K4me2, H3K9me2, or H3K18ac. |
| 申请公布号 |
WO2010120942(A2) |
申请公布日期 |
2010.10.21 |
| 申请号 |
WO2010US31112 |
申请日期 |
2010.04.14 |
| 申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;DAWSON, DAVID W.;KURDISTANI, SIAVASH K.;SELIGSON, DAVID B. |
发明人 |
DAWSON, DAVID W.;KURDISTANI, SIAVASH K.;SELIGSON, DAVID B. |
| 分类号 |
G01N33/574;A61P35/00;C12Q1/68;G01N33/15 |
主分类号 |
G01N33/574 |
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