发明名称 |
NEW USE OF NEFERINE |
摘要 |
<p>The present invention reveals a new use of neferine. Neferine regulates M8 and V1 subtype of transient receptor potential ion channel (TRPM8 and TRPV1), respectively, in mammals, including humans, and can be used for preparing medicaments for treating diseases related to said ion channel (such as hypercryalgesia, Parkinson's disease, painful bladder syndrome, chronic obstructive pulmonary disease, and tumor of skin, prostate, mammary gland, lung, colon, etc.). The potency of neferine in the present invention is higher than that of hexahydrothymol.</p> |
申请公布号 |
WO2010118675(A1) |
申请公布日期 |
2010.10.21 |
申请号 |
WO2010CN71721 |
申请日期 |
2010.04.13 |
申请人 |
INSTITUTE OF CHINESE MATERIA MEDICA, CHINA ACADEMY OF CHINESE MEDICAL SCIENCES;JIANG, TINGLIANG;SUI, FENG;HUO, HAIRU;LI, LANFANG;GUO, SHUYING |
发明人 |
JIANG, TINGLIANG;SUI, FENG;HUO, HAIRU;LI, LANFANG;GUO, SHUYING |
分类号 |
A61K31/4709;A61K9/08;A61K9/14;A61K9/70;A61P1/04;A61P1/18;A61P3/10;A61P11/02;A61P11/06;A61P11/14;A61P13/10;A61P19/02;A61P21/04;A61P25/06;A61P25/16;A61P25/18;A61P29/00;A61P35/04;A61P37/08 |
主分类号 |
A61K31/4709 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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