发明名称 |
GERÄT ZUR VERABREICHUNG VON MEDIKAMENTEN UND GENEN MITTELS ELEKTROPORATION |
摘要 |
<p>A method and apparatus for in vivo electroporation therapy. Using electroporation therapy (EPT) as described in the invention, tumors treated by a combination of electroporation using the apparatus of the invention and a chemotherapeutic agent caused regression of tumors in vivo. In one embodiment, the invention provides a method of EPT utilizing low voltage and long pulse length for inducing cell death. One embodiment of the invention includes a system for clinical electroporation that includes a needle array electrode having a "keying" element that determines the set point of the therapy voltage pulse and/or selectable array switching patterns. A number of electrode applicator designs permit access to and treatment of a variety of tissue sites. Another embodiment provides a laparoscopic needle applicator that is preferably combined with an endoscope for minimally invasive EPT.</p> |
申请公布号 |
DE69841888(D1) |
申请公布日期 |
2010.10.21 |
申请号 |
DE1998641888 |
申请日期 |
1998.07.31 |
申请人 |
GENETRONICS INC. |
发明人 |
HOFMANN, GUNTER A.;DEV, SUKHENDU B.;DIMMER, STEVEN C.;LEVATTER, JEFFREY I.;NANDA, GURVINDER S. |
分类号 |
A61B17/34;A61N1/04;A61B18/14;A61N1/00;A61N1/05;A61N1/30;A61N1/32 |
主分类号 |
A61B17/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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