发明名称 |
Novel anti-DC-SIGN antibodies |
摘要 |
The present invention relates to an antibody for use in treating cancer, wherein the antibody binds to DC-SIGN on the surface of a cancer cell and wherein the binding of the antibody to a DC-SIGN-expressing cancer cell kills the cancer cell. Furthermore, the invention relates to an antibody for use in treating an inflammatory disease or an autoimmune disease, wherein the antibody binds to DC-SIGN on the surface of a dendritic cell and wherein the binding of the antibody to a DC-SIGN-expressing dendritic cell kills the dendritic cell. |
申请公布号 |
EP2241331(A2) |
申请公布日期 |
2010.10.20 |
申请号 |
EP20100007361 |
申请日期 |
2004.12.15 |
申请人 |
ALEXION PHARMACEUTICALS, INC. |
发明人 |
BOWDISH, KATHERINE S.;KRETZ-ROMMEL, ANKE |
分类号 |
A61K45/00;A61K;A61K47/00;A61K47/48;C07K16/00;C07K16/28;C12P21/08;G01N33/53;G01N33/564;G01N33/574 |
主分类号 |
A61K45/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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