发明名称 Novel anti-DC-SIGN antibodies
摘要 The present invention relates to an antibody for use in treating cancer, wherein the antibody binds to DC-SIGN on the surface of a cancer cell and wherein the binding of the antibody to a DC-SIGN-expressing cancer cell kills the cancer cell. Furthermore, the invention relates to an antibody for use in treating an inflammatory disease or an autoimmune disease, wherein the antibody binds to DC-SIGN on the surface of a dendritic cell and wherein the binding of the antibody to a DC-SIGN-expressing dendritic cell kills the dendritic cell.
申请公布号 EP2241331(A2) 申请公布日期 2010.10.20
申请号 EP20100007361 申请日期 2004.12.15
申请人 ALEXION PHARMACEUTICALS, INC. 发明人 BOWDISH, KATHERINE S.;KRETZ-ROMMEL, ANKE
分类号 A61K45/00;A61K;A61K47/00;A61K47/48;C07K16/00;C07K16/28;C12P21/08;G01N33/53;G01N33/564;G01N33/574 主分类号 A61K45/00
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