发明名称 PREPARATION OF ESOMEPRAZOLE MAGNESIUM AND HYDRATES THEREOF
摘要 <p>The present invention includes processes for the preparation of crystalline esomeprazole magnesium dehydrate and/or trihydrate. The present invention includes esomeprazole magnesium dihydrate Form B having a degree of crystallinity of about 70% or less. The present invention includes micronized esomeprazole magnesium dihydrate Form B with a particle size distribution D90 equal to or less than about 10 µm.</p>
申请公布号 EP2240496(A2) 申请公布日期 2010.10.20
申请号 EP20090709236 申请日期 2009.01.30
申请人 DR. REDDY'S LABORATORIES, LTD.;DR. REDDY'S LABORATORIES, INC. 发明人 BOLUGODDU, VIJAYA BHASKAR;CHEEMALAPATI, VENKATA ANNAPURNA SASIKALA;SEERAPU, SIVA PRASAD REDDY;ELATI, RAVI RAM CHANDRASEKHAR;DEVARAKONDA, SURYA NARAYANA;YERRAGUNTLA, SESHA REDDY;KEDIA, UJJWAL
分类号 C07F3/02;C07D401/12 主分类号 C07F3/02
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