USE OF CYTOKINES AND MITOGENS TO INHIBIT PATHOLOGICAL IMMUNE RESPONSES

摘要

Method for ex-vivo inhibition of the production of immunoglobulins in a sample of peripheral blood mononuclear cells (PBMC) by addition of an inhibitory composition (e.g. containing IL-2 or TGF-beta as inhibitor agent) to the cells. Method of treating autoimmune diseases, e.g. systemic lupus erythematosus (SLE), by reintroducing the treated cells to a patient.