发明名称 BIPOLAR TRANS CAROTENOID SALTS AND THEIR USE
摘要 PROBLEM TO BE SOLVED: To provide trans carotenoid salt compounds, methods for making them, methods for solubilizing them and uses of the same. SOLUTION: The compounds include the following structure, and are compounds which are not TSC (trans sodium crocetinate): YZ-TCRO-ZY, wherein Y is a cation, Z is a polar group associated with the cation, and TCRO is a trans-carotenoid skeleton. According to this invention, these compounds are useful in improving diffusivity of oxygen between red blood cells and body tissues in mammals including humans. COPYRIGHT: (C)2011,JPO&INPIT
申请公布号 JP2010229137(A) 申请公布日期 2010.10.14
申请号 JP20100110185 申请日期 2010.05.12
申请人 DIFFUSION PHARMACEUTICALS LLC 发明人 GAINER JOHN L;GRABIAK RAYMOND C
分类号 A61P9/00;C07C403/02;A61K31/202;A61P9/10;A61P11/00;A61P11/06;A61P15/14;A61P25/00;A61P25/28;C07C57/13;C07C69/602;C07C305/14;C07C403/04;C07F9/113 主分类号 A61P9/00
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