| 发明名称 |
INHIBITORS OF S-ADENOSYL-L-METHIONINE DECARBOXYLASE |
| 摘要 |
Novel mechanism-based inhibitors of S-adenosyl-L-methionine decarboxylase are provided. These compounds of formula (1) inhibit the life cycle of trypanosomes, and are useful to treat subjects infected with African trypanosomes. The invention includes pharmaceutical compositions and methods of using the compounds of formula (1).
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| 申请公布号 |
US2010261668(A1) |
申请公布日期 |
2010.10.14 |
| 申请号 |
US20080664628 |
申请日期 |
2008.06.13 |
| 申请人 |
XIANG YIBIN;HIRTH BRADFORD;CELATKA CASSANDRA |
发明人 |
XIANG YIBIN;HIRTH BRADFORD;CELATKA CASSANDRA |
| 分类号 |
A61K31/70;C07H19/16 |
主分类号 |
A61K31/70 |
| 代理机构 |
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