发明名称 |
Selective Inhibitors for Cyclin-Dependent Kinases |
摘要 |
This invention provides a class of compounds which are useful for specifically inhibiting cyclin-dependent kinases. This class of compounds finds use in treating diseases resulting from inappropriate activity of cyclin-dependent kinases, including cancer, viral infections (e.g., HIV) neurodegenerative disorders (e.g. Alzheimer's disease), and cardiovascular disorders (e.g. atherosclerosis). Moreover, certain members of this class are particularly useful for inhibiting cyclin-dependent kinase 7 and are especially useful for the treatment of breast cancer.
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申请公布号 |
US2010261683(A1) |
申请公布日期 |
2010.10.14 |
申请号 |
US20090631373 |
申请日期 |
2009.12.04 |
申请人 |
JOGALEKAR ASHUTOSH S;SNYDER JAMES P;LIOTTA DENNIS C;BARRETT ANTHONY G M;COOMBES RCDS;ALI SIMAK;SIWICKA ALEKSANDRA;BRACKOW JAN;SCHEIPER BODO |
发明人 |
JOGALEKAR ASHUTOSH S.;SNYDER JAMES P.;LIOTTA DENNIS C.;BARRETT ANTHONY G.M.;COOMBES RCDS;ALI SIMAK;SIWICKA ALEKSANDRA;BRACKOW JAN;SCHEIPER BODO |
分类号 |
A61K31/635;A61K31/519;A61P35/00;C07D487/04;C12N9/12 |
主分类号 |
A61K31/635 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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