The present invention provides Gd-chelates modified so as to comprise an amino acid unit attached to the chelate via a linker group suitably selected from C2-4alkylene and C3-5alkynylene, and the use of such chelates as an intravascular contrast agent for MRI. Embodiments demonstrate enhanced relaxivity and good levels of signal enhancement.
申请公布号
WO2010056205(A9)
申请公布日期
2010.10.14
申请号
WO2009SG00418
申请日期
2009.11.11
申请人
NANYANG TECHNOLOGICAL UNIVERSITY;AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH;BATES, RODERICK, WAYLAND;GOLAY, XAVIER;YANG, CHANGTONG
