METHOD OF PREDICTING A PREDISPOSITION TO QT PROLONGATION
摘要
<p>The present invention describes an association between genetic polymorphisms in the FAM13A1 (family with sequence similarity 13, member A1) gene and a predisposition to prolongation of the QT interval, and provides related methods for the prediction of such a predisposition, the administration of QT interval- prolonging compounds to individuals having such a predisposition, and determining whether a compound is capable of inducing QT prolongation.</p>
申请公布号
WO2010117937(A1)
申请公布日期
2010.10.14
申请号
WO2010US29931
申请日期
2010.04.05
申请人
VANDA PHARMACEUTICALS, INC.;LAVEDAN, CHRISTIAN;VOLPI, SIMONA;LICAMELE, LOUIS