| 发明名称 |
METHOD OF PREDICTING A PREDISPOSITION TO QT PROLONGATION BASED ON ABCC2 GENE SEQUENCE OR PRODUCT THEREOF |
| 摘要 |
<p>The present invention describes an association between genetic polymorphisms in the ABCC2 gene and a predisposition to prolongation of the QT interval, and provides related methods for the prediction of such a predisposition, the administration of QT interval-prolonging compounds to individuals having such a predisposition, and determining whether a compound is capable of inducing QT prolongation.</p> |
| 申请公布号 |
CA2757723(A1) |
申请公布日期 |
2010.10.14 |
| 申请号 |
CA20102757723 |
申请日期 |
2010.04.05 |
| 申请人 |
VANDA PHARMACEUTICALS, INC. |
发明人 |
LAVEDAN, CHRISTIAN;VOLPI, SIMONA;LICAMELE, LOUIS |
| 分类号 |
C12Q1/68;A61K31/454;A61K31/519;A61K49/00;A61P25/00 |
主分类号 |
C12Q1/68 |
| 代理机构 |
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