| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a material for soft tissue enlargement, comprising fine particles of pH-responsive water-swelling polymer having a particle size of 15-40 μm (before swelling). <P>SOLUTION: The fine particles of pH-responsive water-swelling polymer, having such a particle diameter to instantaneously cause water swelling in a physiological environment having less moisture (e.g. subcutaneous or submucosa), facilitate injection (injected by a finer injection needle), have less risk of transition to another organ due to foreign body reaction after injection, and are suitable for in-vivo implanted material which is subcutaneous or submucosa. In the fine particles of pH-responsive water-swelling polymer, swelling of the particles is completed within 10 minutes after immersion in 10 mM phosphate buff physiological saline solution (pH 7) at 37°C, and an average particle size is 15-40 μm. <P>COPYRIGHT: (C)2011,JPO&INPIT |
