PHARMACEUTICAL COMPOSITIONS FOR ALLEVIATING UNPLEASANT TASTE

摘要

The present invention relates to oral pharmaceutical compositions that alleviate the bitter, unpleasant or metallic taste associated with eszopiclone therapy. The invention relates to pharmaceutical compositions comprising eszopiclone, at least one taste-masking agent and at least one pharmaceutically acceptable excipient. This taste-masked eszopiclone formulation that masks the immediate unpleasant or objectionable taste of eszopiclone is provided in dosage forms suitable for oral administration such as orally disintegrating tablets, bite-dispersion tablets, dispersible tablets, or the like. The invention further relates to a method of countering this unpleasant after-taste of eszopiclone comprising administering to the patients in need thereof a composition devoid of the active agent either along with or subsequently at an appropriate time after administration of taste-masked eszopiclone.