Methods for the modulation of Leishmania major infection in mammals

摘要

Embodiments of the invention include methods for treating an infection of a mammal by an organism, such as Leishmania major by administering an effective amount of an inhibitor of indolamine 2,3-dexygenase (IDO). A preferred inhibitor is 1-methyl-tryptophan (1MT). The treatment can be highly beneficial as a treatment for visceral leishmaniasis.