| 摘要 |
<p>Disclosed is an inhibitor capable of inhibiting protein kinase Ca or ? selectively. A polypeptide represented by the following formula: Phe-Lys-Lys-Gln-Gly-X4-Phe-Ala-Lys-Lys-Lys has a selective inhibitory activity on protein kinase Ca, and a polypeptide represented by the following formula: Arg-Asp-Met-Arg-Asn-Y6-Phe-Asn-Leu-Gly-Val has a selective inhibitory activity on protein kinase C?. In the formulae, X4 and Y6 independently represent Gly, Ala, Val, Leu, Ile, Pro, Phe, Trp, Cys, Met, Asn, Gln, Asp, Glu, Lys, Arg or His.</p> |
