发明名称 |
PIPERIDINE AND PIPERAZINE DERIVATIVES AS AUTOTAXIN INHIBITORS |
摘要 |
The present invention relates to piperidine and pyrazine derivatives according to formulae (Ia), (Ib) and (II) as autotaxin inhibitors and the use of such compounds for the treatment and/or prophylaxis of physiological and/or pathophysiological conditions, which are caused, mediated and/or propagated by increased lysophosphatic acid levels and/or the activation of autotaxin, in particular of different cancers. |
申请公布号 |
CA2757368(A1) |
申请公布日期 |
2010.10.14 |
申请号 |
CA20102757368 |
申请日期 |
2010.03.03 |
申请人 |
MERCK PATENT GMBH |
发明人 |
SCHIEMANN, KAI;SCHULTZ, MELANIE;STAEHLE, WOLFGANG |
分类号 |
C07D211/30;A61K31/4427;A61K31/4523;A61P9/00;A61P25/28;A61P27/02;A61P29/00;A61P35/00;C07D401/06;C07D401/12;C07D401/14;C07D405/06;C07D405/14;C07D413/14;C07D417/14;C07D471/10 |
主分类号 |
C07D211/30 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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