| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a therapeutic drug having a wider application range and higher effect by improving an antisense oligonucleotide to SES in exon 19, 41, 45, 46, 44, 50, 55, 51 or 53 of dystrophin gene. <P>SOLUTION: There are provided an oligonucleotide having a base sequence complementary to nucleotide Nos. 2571-2607, 2578-2592, 2571-2592, 2573-2592, 2578-2596, 2578-2601, 2575-2592, etc., of dystrophin cDNA (Gene Bank accession No. NM_004006.1), and a therapeutic agent for muscular dystrophy containing the oligonucleotide. <P>COPYRIGHT: (C)2011,JPO&INPIT |
