发明名称 SUBSTANCE SPECIFIC TO HUMAN PD-1
摘要 <p><P>PROBLEM TO BE SOLVED: To provide a monoclonal antibody that can deliver a human PD-1 inhibitory signal, a controlling factor of autoimmune diseases and is useful in treating and/or preventing diseases caused by immune abnormalities. <P>SOLUTION: The anti human PD-1 monoclonal antibody is produced from a hybridoma identified by international accession number FERM BP-8392. The antibody selectively recognizes the human PD-1 and membrane protein existing in the cell membrane in which the human PD-1 is expressed, and delivers the human PD-1 inhibitory signal. <P>COPYRIGHT: (C)2011,JPO&INPIT</p>
申请公布号 JP2010229134(A) 申请公布日期 2010.10.14
申请号 JP20100100455 申请日期 2010.04.26
申请人 ONO PHARMACEUT CO LTD;HONJO TASUKU 发明人 HONJO TASUKU;SHIBAYAMA SHIRO;TAKEDA KAZUHIKO;MATSUO MASAYOSHI;YOSHIDA TAKAO;MIYAMOTO MASAKAZU
分类号 C07K16/42;A61K39/395;A61P3/10;A61P25/28;A61P31/00;A61P35/00;A61P37/02;C07K16/28;C12N15/02;C12N15/13;C12P21/08 主分类号 C07K16/42
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