发明名称 |
SUBSTANCE SPECIFIC TO HUMAN PD-1 |
摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide a monoclonal antibody that can deliver a human PD-1 inhibitory signal, a controlling factor of autoimmune diseases and is useful in treating and/or preventing diseases caused by immune abnormalities. <P>SOLUTION: The anti human PD-1 monoclonal antibody is produced from a hybridoma identified by international accession number FERM BP-8392. The antibody selectively recognizes the human PD-1 and membrane protein existing in the cell membrane in which the human PD-1 is expressed, and delivers the human PD-1 inhibitory signal. <P>COPYRIGHT: (C)2011,JPO&INPIT</p> |
申请公布号 |
JP2010229134(A) |
申请公布日期 |
2010.10.14 |
申请号 |
JP20100100455 |
申请日期 |
2010.04.26 |
申请人 |
ONO PHARMACEUT CO LTD;HONJO TASUKU |
发明人 |
HONJO TASUKU;SHIBAYAMA SHIRO;TAKEDA KAZUHIKO;MATSUO MASAYOSHI;YOSHIDA TAKAO;MIYAMOTO MASAKAZU |
分类号 |
C07K16/42;A61K39/395;A61P3/10;A61P25/28;A61P31/00;A61P35/00;A61P37/02;C07K16/28;C12N15/02;C12N15/13;C12P21/08 |
主分类号 |
C07K16/42 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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