发明名称 MACROCYCLIC AMINO ACID DERIVATIVES FOR TARGETING CANCER TISSUES AND RADIOACTIVE OR NON-RADIOACTIVE LABELED COMPOUND THEREOF
摘要 PURPOSE: An amino acid derivative containing microcycle structure targeting cancer cells and radioactive or non-radioactive metal complex compound is provided to easily make an image of cancer cell site by targeting. CONSTITUTION: A microcyclic amino acid derivative is denoted by chemical formula 1. A complex compound is prepared by binding radioactive metal or non-radioactive metal with microcyclic amino acid derivative or pharmaceutically acceptable salt thereof. The radioactive or non-radioactive metal is Cr, Fe, Co, Ni, Cu, Ga, Sr, Y, Zr, Mo, Tc, Ru, Rh, Pd, Cd, In, Sn, Ba, La, Sm, Gd, Dy, Ho, Lu, Re, Ir, Pb or Bi. A drug for imaging cancer contains the microcyclic amino acid derivative and complex compound of radioactive metal or non-radioactive metal.
申请公布号 KR20100110670(A) 申请公布日期 2010.10.13
申请号 KR20090029126 申请日期 2009.04.03
申请人 SNU R&DB FOUNDATION 发明人 JEONG, JAE MIN;SHETTY DINESH;LEE, DONG SOO;CHUNG, JUNE KEY;LEE, MYUNG CHUL
分类号 C07D255/02;C07D255/00 主分类号 C07D255/02
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