发明名称 |
TREATMENT AND PROPHYLAXIS OF AMYLOIDOSIS |
摘要 |
Methods useful for effecting prophylaxis or treatment of amyloidosis, including AA Amyloidosis and AL amyloidosis, by administering peptides comprising neoepitopes, such as AA fragments from a C-terminal region of AA, and antibodies specific for neoepitopes of aggregated amyloid proteins, for example, antibodies specific for the C-terminal region of AA fibrils. Antibodies for inhibition of formation and/or increasing clearance of amyloid deposits in a patient thus effecting prophylaxis or treating amyloid disease. |
申请公布号 |
EP2237803(A2) |
申请公布日期 |
2010.10.13 |
申请号 |
EP20080867535 |
申请日期 |
2008.12.29 |
申请人 |
ELAN PHARMACEUTICALS INC. |
发明人 |
SCHENK, DALE, B.;SEUBERT, PETER, A.;WALL, JONATHAN;SALDANHA, JOSE |
分类号 |
C12P21/08;A61P43/00;C07K16/18 |
主分类号 |
C12P21/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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