发明名称 |
NOVEL N-(2-AMINO-PHENYL)-AMIDE DERIVATIVES |
摘要 |
<p>The present invention provides novel compounds of the general formula (I) and pharmaceutically acceptable salts thereof, processes for the manufacture of these novel compounds and medicaments containing such compounds. The compounds of the present invention show anti-proliferative and differentiation-inducing activity, which results in inhibition of tumor cell proliferation, induction of apoptosis and inhibition of invasion. The invention also covers the use of such compounds for the treatment of diseases such as cancer and for the manufacture of corresponding medicaments.</p> |
申请公布号 |
EP2238103(A1) |
申请公布日期 |
2010.10.13 |
申请号 |
EP20090705916 |
申请日期 |
2009.01.19 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
CHEN, LI;HE, YUN;WONG, JASON CHRISTOPHER |
分类号 |
C07C237/20;A61K31/167;A61K31/255;A61K31/27;A61K31/275;A61K31/4453;A61K31/541;A61P35/02;C07C255/60;C07C271/28;C07C309/66;C07D213/75;C07D295/13;C07D417/12 |
主分类号 |
C07C237/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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