发明名称 |
Protein-based methods and compositions for the diagnosis of colorectal adenocarcinoma |
摘要 |
Protein-based methods and compositions for the diagnosis of colorectal adenocarcinoma are disclosed. A method for indentifying cell-surface proteins, which are transmembrane proteins or proteins with a signal peptide and which are over-expressed in colorectal cancer (CRC) is disclosed. Biomarkers found with this method, diagnostic methods using them and contrast agents directed to them for use in magnetic resonance imaging (MRI) and/or magnetic photon imaging (MPI) are disclosed.
The methods and biomarkers allow for differentiating progressive (high-risk) CRC (adenocarcinomas) from non-progressive (low-risk) colorectal adenomas. |
申请公布号 |
EP2239577(A1) |
申请公布日期 |
2010.10.13 |
申请号 |
EP20090157464 |
申请日期 |
2009.04.07 |
申请人 |
VERENIGING VOOR CHRISTELIJK HOGER ONDERWIJS, WETENSCHAPPELIJK ONDERZOEK EN PATIENTENZORG |
发明人 |
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分类号 |
G01N33/574;A61K49/00;C07K14/00 |
主分类号 |
G01N33/574 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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