PROCESS FOR PRODUCTION OF SERINE DERIVATIVE, AND PROTEIN FOR USE IN THE PROCESS

摘要

It is an object of the present invention to provide a novel method for generating a serine derivative and an optically active isomer thereof by a convenient technique, and an enzyme and the like used for this. In the presence of the following protein (A) and/or (B) having an enzymatic activity, a certain ±-amino acid is reacted with a certain aldehyde to form a certain serine derivative:
(A) a protein having the amino acid sequence of SEQ ID NO:5, and
(B) a protein having an amino acid sequence comprising mutation of one or several amino acids which is selected from the group consisting of substitution, deletion, insertion and addition in the amino acid sequence of SEQ ID NO:5 and having an activity to catalyze the reaction to form the serine derivative.