发明名称 |
Compositions and methods for treating collagen-mediated diseases |
摘要 |
A drug product comprising a combination of highly purified collagenase I and collagenase II from Colostridium histolyticum is disclosed. The drug product includes collagenase I and collagenase II in a ratio of about 1 to 1, with a purity of greater than at least 95%. The invention further disclosed improved fermentation and purification processes for preparing the said drug product. |
申请公布号 |
US7811560(B2) |
申请公布日期 |
2010.10.12 |
申请号 |
US20070699302 |
申请日期 |
2007.01.29 |
申请人 |
AUXILIUM US HOLDINGS, LLC |
发明人 |
SABATINO GREGORY L.;DEL TITO, JR. BENJAMIN J.;BASSETT PHILLIP J.;THARIA HAZEL A.;HITCHCOCK ANTONY G. |
分类号 |
A61K38/46 |
主分类号 |
A61K38/46 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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