发明名称 METHODS FOR PREDICTING THE RISK OF DIABETIC NEPHROPATHY USING GENETIC MARKERS AND ARRAYS CONTAINING THE SAME
摘要 A method for detecting a Chinese diabetic subject suffering from, at risk for developing, or suspected of suffering from a nephropathy. The method includes determining whether a sample from the subject has at least one of the following polymorphic sequences: an I/D genotype of an ACE gene, an M235T genotype of an AGT gene, a (CA)n-5′(z−2) genotype of an ALR2 gene, an C106T genotype of an ALR2 gene in the promoter region, a G-308A genotype of a TNF-α gene, or a complement thereof, provided that the ALR2 gene cannot be used alone, in which the presence of the polymorphic sequence indicates the subject suffering from, at risk for suffering from a nephropathy. An array for detecting a Chinese diabetic subject suffering from, or at risk for suffering from, a nephropathy.
申请公布号 US2010255495(A1) 申请公布日期 2010.10.07
申请号 US20100816774 申请日期 2010.06.16
申请人 THE CHINESE UNIVERSITY OF HONG KONG 发明人 CHAN JULIANA C.N.;NG MAGGIE C.Y.;SO WING YEE
分类号 C12Q1/68;C12N9/02;C12N9/10;C12N15/12;C12N15/28 主分类号 C12Q1/68
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