| 发明名称 |
METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF KRAS BY ASYMMETRIC DOUBLE-STRANDED RNA |
| 摘要 |
This invention relates to compounds, compositions, and methods useful for reducing KRAS target RNA and protein levels via use of Dicer substrate siRNA (DsiRNA) agents possessing asymmetric end structures. |
| 申请公布号 |
CA2757613(A1) |
申请公布日期 |
2010.10.07 |
| 申请号 |
CA20102757613 |
申请日期 |
2010.04.05 |
| 申请人 |
DICERNA PHARMACEUTICALS, INC. |
发明人 |
BROWN, BOB D. |
| 分类号 |
A61K31/713;C07H21/02;C12N5/00;C12P19/34 |
主分类号 |
A61K31/713 |
| 代理机构 |
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