发明名称 CINAMIC COMPOUNDS AND DERIVATIVES THEREFROM FOR THE INHIBITION OF HISTONE DEACETYLASE
摘要 The invention relates to a compound represented by the following formula (I): and pharmaceutically acceptable salts, stereoisomers, enantiomers, prodrugs and solvates thereof. The compounds are useful as an agent for enhancing the neurite outgrowth and preventing or treating of diseases associated with HDAC in particular, tumor or cell proliferative diseases. In particular, the compounds of the invention can be used as an agent for anti-cancer, anti-diabetic, and anti-neurodegenerative diseases such as Alzheimer's disease, Huntington's disease, Spinocerebellar Ataxias (SCA), and human spinal muscular atrophy (SMA).
申请公布号 US2010256401(A1) 申请公布日期 2010.10.07
申请号 US20090418373 申请日期 2009.04.03
申请人 NATUREWISE BIOTECH & MEDICALS CORPORATION 发明人 HUANG CHUNG-YANG;CHEN CHIA-NAN;HUANG WEI-JAN;LIN CHIA-WEI;HUANG JING-SHI;CHI LI-LING;CHEN AI-LING;LEE CHI-YUN;HUANG YU-CHEN
分类号 A61K31/343;A61K31/16;A61K31/192;A61P35/00;C07C69/736;C07C259/06;C07D307/81 主分类号 A61K31/343
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