发明名称 |
METHOD OF PRODUCING LYMPHOCYTES |
摘要 |
A method of producing lymphocytes characterized by comprising the step of culturing lymphocytes in the presence of a modified recombinant fibronectin fragment which has overlapping parts of the heparin-binding domain of fibronectin. This method makes it possible to achieve a high cell proliferation rate. The lymphocytes obtained thereby are appropriately usable in, for example, adoptive immunotherapy and, therefore, expected as highly useful in the clinical field. Moreover, a novel modified recombinant fibronectin fragment is provided.
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申请公布号 |
US2010255578(A1) |
申请公布日期 |
2010.10.07 |
申请号 |
US20070303911 |
申请日期 |
2007.06.07 |
申请人 |
MURAKI NOBUKO;IDENO MITSUKO;NAGAMINE KINUKO;TAKASHIMA FUYUKO;KOBAYASHI EIJI;KATO AKIKO;MARUI TAKAHIRO;SAGAWA HIROAKI;ENOKI TATSUJI;KATO IKUNOSHIN |
发明人 |
MURAKI NOBUKO;IDENO MITSUKO;NAGAMINE KINUKO;TAKASHIMA FUYUKO;KOBAYASHI EIJI;KATO AKIKO;MARUI TAKAHIRO;SAGAWA HIROAKI;ENOKI TATSUJI;KATO IKUNOSHIN |
分类号 |
C12N5/078;C07H21/00;C07K14/78;C12N5/0783 |
主分类号 |
C12N5/078 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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