发明名称 |
COMPOSITIONS OF CHOLINESTERASE INHIBITORS |
摘要 |
The present invention is directed to compositions, methods of use, and processes for the synthesis related to 3-((S)-1-(dimethylamino)ethyl)phenyl methyl-((R)-1-phenylpropan-2 yl)carbamate, and its pharmaceutically acceptable salt forms, including the hydrogen fumarate salt. The present invention also relates to a novel form polymorph of 3-((S)-1-(dimethylamino)ethyl)phenylmethyl-((R)-1-phenylpropan-2 yl)carbamate, characterized by a unique X-ray diffraction pattern and Differential Scanning Calorimetry profile, as well a unique crystalline structure.
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申请公布号 |
US2010256229(A1) |
申请公布日期 |
2010.10.07 |
申请号 |
US20100753567 |
申请日期 |
2010.04.02 |
申请人 |
COLUCID PHARMACEUTICALS, INC. |
发明人 |
DU SHOUCHENG;ANDERSEN MARC W.;COUGHLIN DANIEL;KOLCHINSKI ALEXANDER |
分类号 |
A61K31/27;A61P1/00;A61P9/10;A61P25/16;A61P25/28;A61P25/34;A61P27/06;C07C271/44 |
主分类号 |
A61K31/27 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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