摘要 |
<p>A system for releasing and sampling analyte material from a target surface, e.g., for analysis, includes a sampling probe that applies irrigation fluid and ultrasonic or vibrational energy to the target, and aspirates desorbed material into a pick-up conduit. The irrigation fluid is provided at the site by an irrigation conduit or capillary co-located with or coaxially disposed about the inlet of the pick-up, and a suction source at the distal end of the pick-up capillary aspirates analyte which has been released from the target into the irrigation fluid, thus efficiently sampling a broad range of materials from an arbitrary target to produce an analyzable effluent analyte stream. The effluent analyte stream may be ionized and provided to the inlet of an ion-type analysis instrument, or may be fed directly to an instrument such as a flow cytometer, IR or fluorescence spectrophotometer, or other analyzer.</p> |