发明名称 |
3-[1,4]OXAZEPANE-4-PYRIMIDONE DERIVATIVES |
摘要 |
<p>A compound represented by the formula (I) or a pharmaceutically acceptable salt thereof: wherein Z represents nitrogen atom, C-F or the like; R1 represents a C1-C3 alkyl group; Y represents oxygen atom or N-R7; R2, R3, R4, R5, R6 and R7 each independently represents hydrogen atom, a C1-C6 alkyl group, or a group represented by the formula (II): which is used for preventive and/or therapeutic treatment of a disease caused by tau protein kinase 1 hyperactivity such as a neurodegenerative diseases (e.g. Alzheimer disease).</p> |
申请公布号 |
WO2010114179(A1) |
申请公布日期 |
2010.10.07 |
申请号 |
WO2010JP56346 |
申请日期 |
2010.04.01 |
申请人 |
MITSUBISHI TANABE PHARMA CORPORATION;SANOFI-AVENTIS;WATANABE, KAZUTOSHI;NAKAYAMA, KAZUKI;SAKAI, DAIKI |
发明人 |
WATANABE, KAZUTOSHI;NAKAYAMA, KAZUKI;SAKAI, DAIKI |
分类号 |
C07D401/14;A61K31/551;A61K31/553;A61P25/00;A61P35/00;C07D403/14;C07D413/14 |
主分类号 |
C07D401/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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