发明名称 |
Conjugate Molecule Compounds With Enhanced Cell Uptake Activity |
摘要 |
This invention relates to a conjugate molecule comprising at least one first portion (I) comprising a carrier sequence and at least one second portion (II) comprising at lest one antitumor drug molecule or a protease inhibitor molecule said conjugate molecule comprising D-enantiomeric amino acids in its portion (I). Furthermore, the invention relates to pharmaceutical compositions containing said conjugate molecule as well as to the use of said conjugate molecule for therapeutic treatment. Methods for improving cell permeability or water solubility are disclosed as well.
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申请公布号 |
US2010256041(A1) |
申请公布日期 |
2010.10.07 |
申请号 |
US20090607816 |
申请日期 |
2009.10.28 |
申请人 |
BONNY CHRISTOPHE;COQUOZ DIDIER |
发明人 |
BONNY CHRISTOPHE;COQUOZ DIDIER |
分类号 |
A61K38/06;A61K38/07;A61K38/08;A61K38/16;A61P31/04;A61P31/12;A61P31/18;A61P33/02;A61P35/00;C07K5/08;C07K5/10;C07K7/06;C07K7/08;C07K14/00 |
主分类号 |
A61K38/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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