MTOR-TARGETED SIRNA HAVING AN INTERSPECIFIC CROSS REACTION, RECOMBINATION VECTOR CONTAINING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME

摘要

The present invention relates to an mTOR-targeted siRNA having an interspecific cross reaction, a recombination vector containing same, and a pharmaceutical composition containing same as an active ingredient. The mTOR-targeted siRNA has a complementary sequence with respect to a portion of the mTOR gene, and thus can decay mRNA of the mTOR gene, or inhibit the translation of mRNA. Therefore, the mTOR-targeted siRNA of the present invention can prevent or treat a wide variety of mTOR-targeted diseases such as cancer, neurodegenerative disease, autoimmune disease, infectious diseases, heart disease, Crohn's disease, can prevent aging, and is especially useful in the prevention or treatment of cancer.