发明名称 |
ANTI-BIOFILM CARBONATE COMPOUNDS FOR USE IN ORAL CARE COMPOSITIONS |
摘要 |
The present invention includes oral care compositions and methods for inhibiting growth and formation of oral biofilms by quorum sensing inhibition and/or bactericidal activity. In some embodiments, the present invention discloses an oral care composition including a therapeutically effective amount of at least one carbonate compound of Formula (1) and at least one excipient: wherein, R1 and R2 are independently: an aliphatic radical; a hydroxyaliphatic radical; or an aryl radical. In some embodiments, the present invention discloses a method of providing oral care benefits including applying to an oral cavity an oral care composition containing a therapeutically effective amount of at least one carbonate compound of Formula (1) and at least one excipient. In some embodiments, the present invention discloses a method of up- regulating or down-regulating periodontal disease metabolites including applying to an oral cavity an oral care composition containing a therapeutically effective amount of at least on carbonate compound of Formula (1) and at least one excipient. |
申请公布号 |
WO2010114533(A1) |
申请公布日期 |
2010.10.07 |
申请号 |
WO2009US39140 |
申请日期 |
2009.04.01 |
申请人 |
COLGATE-PALMOLIVE COMPANY;TRIVEDI, HARSH, M.;MIKSA, DAVIDE;XU, TAO |
发明人 |
TRIVEDI, HARSH, M.;MIKSA, DAVIDE;XU, TAO |
分类号 |
A61K31/265;A61P1/02;A61P31/04 |
主分类号 |
A61K31/265 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|