发明名称 CRYSTALLINE FORM OF A PHENYLETHANOLAMINE, THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME
摘要 The subject-matter of the invention is the B form of ethyl [(7S)-7-[(2R)-2-(3-chlorophenyl)-2-hydroxyethylamino]-5,6,7,8-tetrahydronaphth-2-yloxy]acetate hydrochloride, of use as a medicament, which exhibits in particular the following physical characteristics: characteristic IR absorption peaks (cm<SUP>-1</SUP>): 2780, 2736, 1722, 1211; melting point: 129+/-2° C.; characteristic lines of the powder X-ray diffraction diagram (to within 0.1(2theta)): 7.69, 9.83, 13.95, 16.58, 18.70, 20.40, 21.57, 23.40, 24.15 and 25.64. The product can be obtained by salification of the base or recrystallization of the salt from an alcohol.
申请公布号 PL206680(B1) 申请公布日期 2010.09.30
申请号 PL20020368055 申请日期 2002.06.27
申请人 SANOFI-AVENTIS 发明人 CARON ANTOINE;MONNIER OLIVIER;OBERT SABRINA;ROCHE JEROME;ZIRI ISABELLE
分类号 A61P1/00;C07C217/74;A61K31/215;A61K31/216;A61K31/24;A61P25/24;C07C213/10;C07C219/26;C07C227/18;C07C229/50 主分类号 A61P1/00
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