MONOCLONAL ANTIBODY AGAINST A CONSERVED DOMAIN OF M2E POLYPEPTIDE IN INFLUENZA VIRUSES

摘要

The invention provides monoclonal antibodies and related binding proteins that bind specifically to the ectodomain of the M2 membrane protein of influenza A virus. The monoclonal antibodies and related binding proteins are useful for the detection of influenza A virus, including H5 subtypes such as the pathogenic H5N1 avian influenza virus. Accordingly, the invention provides means for the diagnosis, surveillance, treatment and prevention of dangerous viral infections.