发明名称 COMPOUND AND USE THEREOF IN THE TREATMENT OF AMYLOIDOSIS
摘要 The present invention relates to compounds of formula (I) for stabilizing the tetrameric form of transthyretin, compounds for use in the treatment or prevention of amyloidosis, and agents and medicaments comprising such compounds. wherein X, Y, R1, R2, R3, R4, m, n, p, q, and the linker are as defined herein.
申请公布号 US2010249233(A1) 申请公布日期 2010.09.30
申请号 US20100728361 申请日期 2010.03.22
申请人 PEPYS MARK BRIAN;LEY STEVEN VICTOR;MORRISON ANGUS JOHN;BELLOTTI VITTORIO;WOOD STEPHEN;KOLSTOE SIMON;SMITH MARTIN 发明人 PEPYS MARK BRIAN;LEY STEVEN VICTOR;MORRISON ANGUS JOHN;BELLOTTI VITTORIO;WOOD STEPHEN;KOLSTOE SIMON;SMITH MARTIN
分类号 A61K31/196;A61P43/00;C07C229/58 主分类号 A61K31/196
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