SOLID PREPARATION

摘要

Disclosed is a solid preparation (1) which comprises: a drug-containing part (2) that contains a cationic drug; a gel-forming layer (4) that contains an anionic polymer and covers the drug-containing part (2), while forming a gel by absorbing water; and if necessary, an intermediate layer (3) that is interposed between the drug-containing part (2) and the gel-forming layer (4). In the solid preparation (1), the dissolvability of a drug is improved by having the drug-containing part (2) and/or the intermediate layer (3) contain an acid component (such as tartaric acid and citric acid). The gel-forming layer (4) may be formed from a carboxyvinyl polymer and a polyvalent metal compound. The gel-forming layer (4) may be covered with a surface layer (adhesion preventing layer) (5).