发明名称 1,1,1-TRIFLUORO-2-HYDROXYPROPYL COMPOUNDS
摘要 The present invention relates to compounds of formula I wherein R1a to R1e and R2 to R5 are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are glucocorticoid receptor antagonists useful for the treatment and/or prevention of diseases such as diabetes, dyslipidemia, obesity, hypertension, cardiovascular diseases, adrenal imbalance or depression.
申请公布号 US2010249139(A1) 申请公布日期 2010.09.30
申请号 US20100727269 申请日期 2010.03.19
申请人 HUNZIKER DANIEL;LERNER CHRISTIAN;MUELLER WERNER;SANDER ULRIKE OBST;PFLIEGER PHILIPPE;WALDMEIER PIUS 发明人 HUNZIKER DANIEL;LERNER CHRISTIAN;MUELLER WERNER;SANDER ULRIKE OBST;PFLIEGER PHILIPPE;WALDMEIER PIUS
分类号 C07D241/16;A61K31/381;A61K31/437;A61K31/44;A61K31/444;A61K31/47;A61K31/4965;A61K31/498;A61K31/501;A61K31/506;A61P3/00;A61P3/10;C07D213/55;C07D213/63;C07D215/14;C07D217/04;C07D241/36;C07D333/22;C07D401/12;C07D413/12;C07D471/04 主分类号 C07D241/16
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