METHOD FOR PREPARATION OF HEPARIN FROM MUCOSA

摘要

This invention relates to a method for the preparation of heparin by enzymatic digestion of raw mucosa, and to protein hydrolysate and heparin thus produced. The method does not require the use of preservatives, and comprises a fast hydrolysis step reducing the viscosity, yielding a mucosa hydrolysate from which the heparin can be isolated with a resin contacting step, as a resin bound heparin. Heparin can be extracted from the resin bound heparin, and high yields as high as 50,000 Units per kg can be obtained.