RNAi sequences against the Influenza A segment 1 PB2 gene and uses thereof as anti-viral therapeutic

摘要

An siRNA comprising a first nucleic acid sequence selected from SEQ ID NOs: 7 and 5503-5506 and a second nucleic acid that is at least 84% complementary to the first nucleic acid sequence, wherein the siRNA has a duplex region from 15-60 nucleotides in length. The siRNA is targeted towards the Influenza A segment 1 PB2 gene and is used as a therapeutic against Influenza respiratory infection.