发明名称 METHOD FOR MEASUREMENT OF CONCENTRATION OF ANTIGEN
摘要 The object of the present invention is to provide a detection method that can detect an antigen even if the target antigen has a low molecular weight in a simpler, more efficient, and more stable manner and with higher sensitivity. The detection of the antigen is carried out by using a fusion protein comprising a polypeptide containing a VH domain of an antibody; a given protein; a linker peptide; a partner protein having an activity of binding to the protein and capable of detecting binding to the protein; and a polypeptide containing a VL domain of the antibody; in this order or in inverse order to this order, wherein the presence or absence of the binding of the polypeptide containing a VH domain and the polypeptide containing a VL domain to the antigen induces the presence or absence of the binding of the protein and the partner protein.
申请公布号 US2010248267(A1) 申请公布日期 2010.09.30
申请号 US20080671002 申请日期 2008.07.30
申请人 JAPAN SCIENCE AND TECHNOLOGY AGENCY 发明人 UEDA HIROSHI;KOJIMA MIKI
分类号 G01N33/569;C07H21/00;C07K16/00;C12N1/21;C12N9/86;C12N15/74;G01N33/566 主分类号 G01N33/569
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