发明名称 |
METHODS AND COMPOSITIONS FOR ACTIVATED PROTEIN C WITH REDUCED ANTICOAGULANT PROPERTIES |
摘要 |
This invention relates to a novel form of protein C or activated protein C. More specifically, the invention is directed to a variant of protein C that is activated at a higher rate than wild-type or other variants and produces an activated protein C with reduced anticoagulant properties while retaining the protective anti-inflammatory and anti-apoptotic properties of wild-type activated protein C. This novel APC variant will be beneficial for treating inflammatory and apoptotic disorders with a reduced risk for bleeding.
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申请公布号 |
US2010247511(A1) |
申请公布日期 |
2010.09.30 |
申请号 |
US20100796623 |
申请日期 |
2010.06.08 |
申请人 |
SAINT LOUIS UNIVERSITY |
发明人 |
REZAIE ALIREZA R.;YANG LIKUI |
分类号 |
A61K38/48;A61P9/10;A61P25/00;A61P25/28;A61P29/00 |
主分类号 |
A61K38/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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