发明名称 Novel synthetic peptide vaccines for HIV: the CBD epitope as an effective immunogen to elicit broadly neutralizing antibodies against HIV
摘要 The present invention relates to peptides, referred to as CBD-1, CBD-2, CBM-1/TH-1, CBM-1/TH-2, CBM-2/TH-1, CBM-2/TH-2 and C-20 peptides, which are antigenic and elicit protective immune response against HIV infection. Compositions, pharmaceutical compositions and vaccines comprising these antigenic peptides are also encompassed by the present invention, as well as neutralizing antibodies which inhibit infection of primary CD4+ T lymphocytes by various HIV isolates. Methods for diagnosis of HIV are also disclosed.
申请公布号 US2010247618(A1) 申请公布日期 2010.09.30
申请号 US20080073887 申请日期 2008.03.11
申请人 INSTITUT PASTEUR 发明人 HOVANESSIAN ARA;BRIAND JEAN PAUL;MULLER SYLVIANE;KRUST BERNARD;SVAB JOSETTE;SAID ELIAS
分类号 A61K9/127;A61K38/08;A61K38/10;A61K38/12;A61K38/14;A61K38/16;A61K39/00;A61K39/21;A61P31/18;C07H21/04;C07K7/06;C07K7/08;C07K14/00;C07K14/16;C07K14/435;C07K16/00;C07K16/10;C12Q1/70;G01N33/569;G01N33/68 主分类号 A61K9/127
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