摘要 |
<p>The present invention relates to a compound of Formula (I): wherein: R1 is H or C1-2 alkyl; R2 is H or C1-3 alkyl; R3 and R4 are each independently H or C1-2 alkyl, where the alkyl may be substituted with one to three of the same or different substituents selected from R10; R5 is H, hydroxy, C1-2 alkyl, or OCH3; and R10 is F or Cl, or a pharmaceutically acceptable salt or ester thereof.</p> |
申请人 |
BANYU PHARMACEUTICAL CO., LTD.;VERTEX PHARMACEUTICALS INCORPORATED;BINCH, HAYLEY;HASHIMOTO, MASAYA;IWAMA, TOSHIHARU;KAWANISHI, NOBUHIKO;MORTIMORE, MICHAEL;OHKUBO, MITSURU;SUNAMI, TOMOKO |
发明人 |
BINCH, HAYLEY;HASHIMOTO, MASAYA;IWAMA, TOSHIHARU;KAWANISHI, NOBUHIKO;MORTIMORE, MICHAEL;OHKUBO, MITSURU;SUNAMI, TOMOKO |