ANGIOGENESIS METHODS, MEDICAMENTS AND AGENTS

摘要

A method of modulating angiogenesis in an individual in need thereof comprising administering an agent that modulates at least one function or activity of TeI to the individual. A method of identifying a modulator of angiogenesis comprising: a) providing TeI or a portion or a variant thereof, said portion or variant being capable of binding to at least one of DNA and CtBP; b) providing a test agent; c) assessing whether the test agent modulates at least one function or activity of TeI; and d) assessing whether the test agent modulates angiogenesis in an assay for angiogenesis.