发明名称 SNP DETECTION BY MELT CURVE CLUSTERING
摘要 Systems, methods and apparatus for an automated analysis of a collection of melt curves is provided. The analysis can identify certain characteristics of double stranded nucleotide sequences (e.g. DNA or other nucleotide sequences) which were melted. For example, a variation (e.g. a mutation) in the sequences (also called amplicons) may be determined from the analysis. The amplicons may be amplified via any amplification mechanism, such as PCR or Ligase chain reaction (LCR). The automated analysis can include identifying a melt region, normalizing a melt curve, and clustering melt curves.
申请公布号 US2010250145(A1) 申请公布日期 2010.09.30
申请号 US20100713076 申请日期 2010.02.25
申请人 BIO-RAD LABORATORIES, INC. 发明人 HOUSER THOMAS
分类号 G06F19/00 主分类号 G06F19/00
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